Excitatory But Not Inhibitory Synaptic Transmission Is Reduced in Lethargic (Cacnb4) and Tottering (Cacna1a) Mouse Thalami
نویسندگان
چکیده
SARAH J. CADDICK, CHUNSHENG WANG, COLIN F. FLETCHER, NANCY A. JENKINS, NEAL G. COPELAND, AND DAVID A. HOSFORD Department of Neurology, Medical College of Virginia, Richmond, Virginia 23298; Department of Medicine, Division of Neurology and Department of Neurobiology, Duke University Medical Center and Durham Veterans Affairs Medical Center, Durham, North Carolina 27705; and Mammalian Genetics Laboratory, Advanced Biosciences Labs, Basic Research Program, National Cancer Institute, Frederick Cancer Research and Development Center, Frederick, Maryland 21702
منابع مشابه
Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami.
Excitatory but not inhibitory synaptic transmission is reduced in lethargic (Cacnb4(lh)) and tottering (Cacna1atg) mouse thalami. Recent studies of the homozygous tottering (Cacna1atg) and lethargic mouse (Cacnb4(lh)) models of absence seizures have identified mutations in the genes encoding the alpha1A and beta4 subunits, respectively, of voltage-gated Ca2+ channels (VGCCs). beta subunits norm...
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